Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50057583'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057583(4-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory concentration required to block human recombinant prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89BHBPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Searle Research and Development

Curated by ChEMBL
LigandPNGBDBM50057583(4-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 50.1nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736S4DPubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50057583(4-[3-Difluoromethyl-5-(3-fluoro-4-methoxy-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25B01WPPubMed