Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50297677'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297677(CHEMBL551829 | N-benzyl-4-(4-(methylsulfonyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of human COX2 expressed in baculovirus-infected SF9 cells assessed as inhibition of arachidonic acid-stimulated PGE2 production treated 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z7396PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50297677(CHEMBL551829 | N-benzyl-4-(4-(methylsulfonyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of lipopolysaccharide-stimulated PGE2 production after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z7396PubMed