Compile Data Set for Download or QSAR
Found 12 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM50339185'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid as substrate assessed as reduction in PGH2 conversion to PGG2 by measuring TMPD oxidation ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+3nMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+3nMAssay Description:Tested for inhibitory activity against Prostaglandin G/H synthase 2 from humanMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 5.22E+4nMAssay Description:Inhibitory concentration required for in vitro binding affinity to cholinergic central Nicotinic acetylcholine receptor on rat brain cortex by using ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+6nMAssay Description:Inhibition of COX2-catalyzed prostaglandin biosynthesis after 10 mins of preincubationMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Universitat de Barcelona

Curated by ChEMBL
LigandPNGBDBM50339185((2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+6nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair