Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 1 [11-371]' and Ligand = 'BDBM50328744'
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)copy SMILEScopy InChI
Affinity DataIC50: 4.31E+4nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-SAM by scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)copy SMILEScopy InChI
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of human GST-tagged PRMT1-mediated arginine methylation expressed in Escherichia coli BL21 (DE3) using H4(1-20) and [14C]-AdoMet by scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50328744(7-hydroxy-8-((2-methoxy-5-(vinylsulfonyl)phenyl)di...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of His6x-tagged PRMT1-mediated protein arginine methylation expressed in Escherichia coli BL21 (DE3) using GAR R4 peptide and [14C]-AdoMet...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251JDBPubMed