Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3 [N508S]' and Ligand = 'BDBM178103'
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  55nM IC50: 119nMAssay Description:In brief, the tritiated S-adenosyl-L-methionine (3HSAM, PerkinElmer Life Sciences) was used as the donor of methyl group. The (3H) methylated biotin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765D4HPubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University of Toronto

LigandPNGBDBM178103(MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human PRMT3 assessed as inhibition of methylation activity using biotin-labeled peptide as substrate and [3H]-SAM by scintillation prox...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028TGJPubMed