Found 3 Enz. Inhib. hit(s) with Target = 'Protein arginine N-methyltransferase 3 [N508S]' and Ligand = 'BDBM50427768' TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human PRMT3 (211 to 531) using histone-4 (1 to 24) as substrate by S-adenosylhomocysteine hydrolase-coupled assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataKd: 9.50E+3nMAssay Description:Binding affinity to 6xHis-tagged recombinant human PRMT3 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
