Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM238374'
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Saccharomyces cerevisiae (Baker's yeast))
Centre de Recherche de Gif

LigandPNGBDBM238374(3-(3-Thienyl)-4-cyano-5-(isopropylthio)thiophene-2...)copy SMILEScopy InChI
Affinity DataIC50: 350nMpH: 7.5Assay Description:Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on Wallac Victor fluorimeter from Per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
LigandPNGBDBM238374(3-(3-Thienyl)-4-cyano-5-(isopropylthio)thiophene-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:Assays were realized on 96-well plates, as described for yeast FTase but octyl-D-glucopyranoside (0.18%) was used instead of CHAPS and the solution c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed