BindingDB PrimarySearch

Found 1 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50079976'

Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

BDBM50079976((S)-2-(2-(((2S,3R)-3-methyl-2-(2-(1-(pyridin-4-ylm...)copy SMILEScopy InChI

IC50: 74nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant [Leu68]-RAS1CVIM by FarnesyltransferaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q27P9020PubMed