Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Protein kinase C theta type' and Ligand = 'BDBM25558'
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25558(4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...)copy SMILEScopy InChI
Affinity DataKi:  79nM ΔG°:  -40.1kJ/mole IC50: 70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5C8KPubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25558(4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human PKCtheta by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0FD4PubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM25558(4-arylamino-3-pyridinecarbonitrile, 4p | 5-(3,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.2 T: 2°CAssay Description:All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6NVVPubMed