Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Protein tyrosine phosphatase type IVA 2' and Ligand = 'BDBM50059084'
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))TBA
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of human His6-tagged PRL-2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 peptide as substrate by IMAP-FP as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3JSFPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))TBA
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of human PRL2 expressed in Escherichia coli using TAMRA-Thr-Ala-Asp-Ile-Tyr(PO3H2)-Glu-NH2 substrate by immobilized metal ion affinity-bas...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))TBA
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human His-6-tagged PTP4A2 expressed in Escherichia coli assessed as increase in polarization using TAMRAThr-Ala-Asp-Ile-Tyr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5SBFPubMed
TargetProtein tyrosine phosphatase type IVA 2(Homo sapiens (Human))TBA
LigandPNGBDBM50059084(CHEMBL3393171 | US10308663, Thienopyridone (5))copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMAssay Description:Inhibition of PRL2 (unknown origin) using DiFMUP as fluorogenic phosphate substrate assessed as DiFMUP dephosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9Z8GPubMed