Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Protein-tyrosine kinase 2-beta' and Ligand = 'BDBM50246327'
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of PYK2 by PYK2-LI-COR cellular assayMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of PYK2 assessed as reduction in peptide substrate phosphoryltion by fluorimetric methodMore data for this Ligand-Target Pair
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246327(4-(4-((1R,2R)-2-(dimethylamino)cyclopentylamino)-5...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of GST-tagged pyk2 (unknown origin) assessed as inhibition of poly-Glu-Tyr phosphorylationMore data for this Ligand-Target Pair