Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM12676'
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  540nM ΔG°:  -35.4kJ/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319T41PubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1KQSPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z7322PubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  540nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK19K9PubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Company

LigandPNGBDBM12676(1-(3-Aminobenzisoxazol-5-yl)-3-trifluoromethyl-N-[...)copy SMILEScopy InChI
Affinity DataKi: >6.30E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4B9ZPubMed