Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM14129'
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14129(2-[(2S)-5-carbamimidamido-2-{[(2S)-1-[(2R)-2-(meth...)copy SMILEScopy InChI
Affinity DataKi:  2nM IC50: 45nMAssay Description:Thrombin-catalyzed hydrolysis rates were measured spectrophotometrically using human alpha-thrombin, a chromogenic substrate in aqueous buffer, and a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X0658XPubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14129(2-[(2S)-5-carbamimidamido-2-{[(2S)-1-[(2R)-2-(meth...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BNHPubMed
TargetProthrombin(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14129(2-[(2S)-5-carbamimidamido-2-{[(2S)-1-[(2R)-2-(meth...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Binding affinity to human thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251HN2PubMed