Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM19023'
TargetProthrombin(Homo sapiens (Human))
Amgen

LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Thrombin: In the assay for measuring the inhibition of human thrombin activity buffer (10 mM HEPES buffer, pH 7.4, 2 mM CaCl2) is used. The IC50 is m...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F1921PUS Patent
TargetProthrombin(Homo sapiens (Human))
Amgen

LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q23XJ9PubMed
TargetProthrombin(Homo sapiens (Human))
Amgen

LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FQ9WQGPubMed