BindingDB PrimarySearch

Found 2 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50031706'

Prothrombin(Homo sapiens (Human))TBA

BDBM50031706(4-Guanidino-benzoic acid 4-dimethylcarbamoylmethox...)copy SMILEScopy InChI

Ki: 621nMAssay Description:Vero E6 cells were transfected with mock (pcDNA3.1), TMPRSS2 (pcDNA3.1/TMPRSS2 Uniprot: O15393-1), or TMPRSS2-S441A (pcDNA3.1/TMPRSS2-S441A) using Li...More data for this Ligand-Target Pair

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Details Article
BindingDB Entry DOI: 10.7270/Q2NP27M4PubMed

Prothrombin(Homo sapiens (Human))TBA

BDBM50031706(4-Guanidino-benzoic acid 4-dimethylcarbamoylmethox...)copy SMILEScopy InChI

IC50: 3.16E+4nMAssay Description:Concentration required to inhibit enzymatic cleavage of the chromogenic substrate (H-D-Phe-Pip-Arg-pNA) thrombin in vitro.More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Details
BindingDB Entry DOI: 10.7270/Q2MC8Z12PubMed