Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50249298'
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant thrombin expressed in HEK293 cells using S-2238 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251NKTPubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15F5PubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human thrombin using substrate S-2238 preincubated for 30 mins followed by substrate addition measured after 20 mins by micro plate rea...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300DXPubMed
TargetProthrombin(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(BEVYXXA | CHEMBL512351 | N-(5-chloropyridin-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human thrombin using acromogenic substrate S-2238 preincubated for 30 mins before substrate addition measured after 20 mins by spectrop...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PH4PubMed