Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50111470'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111470(CHEMBL1232944)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of cSrc T338M/S345C mutant (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111470(CHEMBL1232944)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of cSrc T338M mutant (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111470(CHEMBL1232944)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Inhibition of wild type cSrc (251 to 533 residues) (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed