Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM6095'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27942VFPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP05HDPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM6095(3-quinolinecarbonitrile 23 | 4-[(2,4-Dichloro-5-me...)copy SMILEScopy InChI
Affinity DataIC50: 7.70nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43R88PubMed