Found 9 Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM24773' 
Affinity DataIC50: 59nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of wild type RET (unknown origin) by cellular phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding constant for RET kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding constant for RET(M918T) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RET(V804M) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for RET(V804L) kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding constant for RET kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding constant for RET(M918T) kinase domainMore data for this Ligand-Target Pair
