Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50247151'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  0.0196nMAssay Description:Equilibrium binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6F4HPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-inhibitor complex ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1FF5PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Initial binding affinity to wild type human PNPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6F4HPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Albert Einstein College of Medicine of Yeshiva University

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant human PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1FF5PubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate assessed as inhibition constant for slow onset inhibition of enzyme-in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1FF5PubMed
TargetPurine nucleoside phosphorylase(Plasmodium falciparum)
Victoria University of Wellington

Curated by ChEMBL
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP using inosine as substrate by xanthine oxidase coupling enzyme assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1FF5PubMed