Compile Data Set for Download or QSAR
Found 7 Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50397794'
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Akt1 (1 to 480) expressed in Sf9 cells using biotin-GRPRTSSFAEG as substrate after 20 mins by Alpha-screen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation of Akt at S473 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of Akt 1 in human AN3CA cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of Akt 1 in human A2780 cells assessed as phosphorylation of Akt at T308 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of Akt1 in human A2780 cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
ArQule Inc.

Curated by ChEMBL
LigandPNGBDBM50397794(CHEMBL2177827)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt1 in human AN3CA cells assessed as phosphorylation PRAS40 at T246 after 2 hrs by Western Blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G5JPubMed