Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM13216'
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 164nMAssay Description:Inhibition of cRAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z15R6PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Binding constant for RAF1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Binding constant for RAF1 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center for Molecular Medicine of the Austrian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)copy SMILEScopy InChI
Affinity DataKd:  570nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RX99G5PCBioAssay