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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-3' and Ligand = 'BDBM149404'
Target
Receptor tyrosine-protein kinase erbB-3
(Homo sapiens (Human))
Wuxi AppTec
Curated by
ChEMBL
Ligand
BDBM149404
(AVL-301 | CHEMBL3545308 | CNX-419 | CO-1686 | Roci...)
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Affinity Data
IC50: 46nM
Assay Description:
Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISA
More data for this Ligand-Target Pair
Target Info
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MMDB
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UniProtKB/SwissProt
B.MOAD
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Ligand Info
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MCE
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25X2CJZ
PubMed