Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Receptor tyrosine-protein kinase erbB-3' and Ligand = 'BDBM5446'
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R mutant phosphorylation in human H3255 cells preincubated for 2 hrs followed by EGF stimulation for 10 mins by sandwich ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CJZPubMed
TargetReceptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Wuxi AppTec

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)copy SMILEScopy InChI
Affinity DataKd:  1.10E+3nMAssay Description:Binding constant for ERBB3 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed