Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM16673'
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27082B4PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMAssay Description:Average Binding Constant for RIPK2; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69J3TPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for RIPK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TT4RX2PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for RIPK2 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MW2FH1PCBioAssay
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University of Dundee

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to RIPK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed