Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 2' and Ligand = 'BDBM50467984'
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length His/flag-tagged RIPK2 (unknown origin) expressed in baculovirus expression system using fluorescently labeled substrate inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Rattus norvegicus)
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50467984(CHEMBL4293287)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of RIPK2 in rat whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measure...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8VJVPubMed