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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM112474'
Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Amgen Inc.
US Patent
Ligand
BDBM112474
(US8623885, 15)
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Affinity Data
IC50: 3.10nM
pH: 7.6
Assay Description:
The FLT3 inhibitory activity of the CDK4/6-FLT3 inhibitors was determined with a HTRF kinase assay. The FLT3 enzyme (GST-FLT3 fusion) was purchased f...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ06Z1
US Patent