Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM389591'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research Ltd

Curated by ChEMBL
LigandPNGBDBM389591(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research Ltd

Curated by ChEMBL
LigandPNGBDBM389591(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research Ltd

Curated by ChEMBL
LigandPNGBDBM389591(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 258nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4T0SUS Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Vichem Chemie Research Ltd

Curated by ChEMBL
LigandPNGBDBM389591(N'-{2-[(E)-2-(4- isopropylphenyl)vinyl]quinazolin-...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27947ZVPubMed