Found 12 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50250180' 
Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Affinity DataIC50: 91nMAssay Description:Inhibition of human HL60 cells-derived His-tagged FLT3 (564 to 993 residues) expressed in baculovirus infected sf9 cells using poly (4:1 Glu, Tyr) as...More data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM13 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM14 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM4 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM13 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM14 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of Akt phosphorylation at Thr308/Ser473 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MV4-11 cells assessed as inhibition of ERK phosphorylation at Thr202/Tyr204 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
Affinity DataEC50: <10nMAssay Description:Inhibition of FLT3 in human MOLM13 cells assessed as inhibition of STAT5 phosphorylation at Tyr694 site after 4 hrs by immunoblotting analysisMore data for this Ligand-Target Pair
