Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50357591'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of FLT3 using EAIYAAPFAKKK as substrate by radiometric assay in the presence of 200 uM [ATP]More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WD6PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Cylene Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of FLT3 phosphorylation at Tyr591 in human MV-4-11 cells assessed as phospho-FLT3 level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7WD6PubMed