Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein kinase FLT3' and Ligand = 'BDBM50533653'
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50533653(CHEMBL4519741)copy SMILEScopy InChI
Affinity DataIC50: 0.0380nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MQ1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50533653(CHEMBL4519741)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MQ1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50533653(CHEMBL4519741)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged FLT3 (564 to end residues) expressed by baculovirus in Sf21 insect cells measured after 10 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z76SQPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50533653(CHEMBL4519741)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of FLT3 ITD/F691L double mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MQ1PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50533653(CHEMBL4519741)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of FLT3 ITD/D835Y double mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154MQ1PubMed