BindingDB PrimarySearch

Found 10 Enz. Inhib. hit(s) with Target = 'Receptor-type tyrosine-protein phosphatase F' and Ligand = 'BDBM50391109'

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 1.38E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrate by spectrophotometryMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q20K2B5MPubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 1.51E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2CR5XN6PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 1.65E+4nMAssay Description:IC50 values were determined by pNPP assay.More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2PC3122PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 1.80E+4nMAssay Description:Inhibition of human recombinant GST-tagged LAR (catalytic domain 1275 to 1613 residues) expressed in Escherichia coli BL21 (DE3) using pNPP as substr...More data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q2028VWBPubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) using pNPP as substrateMore data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q28917N0PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 2.23E+4nMAssay Description:Inhibition of LAR (unknown origin) assessed as hydrolysis of pNPP to pNP after 30 minsMore data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q2QZ2CTVPubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 2.23E+4nMAssay Description:Inhibition of human GST-tagged LAR D1 (1275 to 1613 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair

PDB MMDB KEGG
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BindingDB Entry DOI: 10.7270/Q23B62P2PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 2.46E+4nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q21C1Z14PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 3.26E+4nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2BR8WM5PubMed

Receptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Nanchang University

Curated by ChEMBL

BDBM50391109(CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...)copy SMILEScopy InChI

IC50: 1.41E+5nMAssay Description:Inhibition of LAR (unknown origin)More data for this Ligand-Target Pair

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BindingDB Entry DOI: 10.7270/Q2MP54XRPubMed

Targets 1 ▿
- Receptor-type tyrosine-protein phosphatase F 10
Publications 10 ▿
- Bioorg Med Chem Lett 29: 1187-1193 (2019) 1
- Eur J Med Chem 166: 178-185 (2019) 1
- Bioorg Med Chem Lett 22: 7440-3 (2012) 1
- Eur J Med Chem 172: 163-173 (2019) 1
- Bioorg Med Chem 23: 4891-8 (2015) 1
- Bioorg Med Chem 23: 38-45 (2014) 1
- Eur J Med Chem 144: 692-700 (2018) 1
- Bioorg Med Chem Lett 24: 4125-8 (2014) 1
- Bioorg Med Chem 23: 7079-88 (2015) 1
- Bioorg Med Chem Lett 24: 1889-94 (2014) 1
Institutions 9 ▿
- [Qilu University of Technology] 2
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
- [Yanbian University, Chinese Academy of Sciences, Qilu University of Technology (Shandong Academy of Sciences), Liaoning Normal University, East China University of Science and Technology, Yanbian University College of Pharmacy, Nanchang University, Jiangnan University] 1
Affinity: 1.4E+4 to 1.4E+5 nM▿
- IC50 10
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 1