Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM17949'
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.2 T: 2°CAssay Description:In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of renin in plasmaMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
Gyeongsang National University (GNU)

Curated by ChEMBL
LigandPNGBDBM17949((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair