Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM29940'
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29940(piperidine-1-carboxamide, 21c)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.0 T: 2°CAssay Description:The activity of renin inhibitors in vitro was measured using the FRET assay, which was carried out in flat-bottom white opaque microtiter plates. The...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21VXVPubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29940(piperidine-1-carboxamide, 21c)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of trypsin-activated human recombinant reninMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V20PubMed
TargetRenin(Homo sapiens (Human))
Vitae Pharmaceuticals

LigandPNGBDBM29940(piperidine-1-carboxamide, 21c)copy SMILEScopy InChI
Affinity DataIC50: 315nMAssay Description:Inhibition of human recombinant renin assessed as decrease in plasma renin activity by competitive radioimmunoassay in presence of human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7V20PubMed