Compile Data Set for Download or QSAR
Found 16 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM420297'
TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:SARS-CoV-2 3CLpro expression and purification is based on a published procedure and our modified protocol is found in the supplementary file. A highl...More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Functional H2 receptor antagonistic activity in vitro assay on the isolated spontaneously beating guinea-pig right atriumMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Recombinant SARS-CoV-2 Mpro was expressed and purified from Escherichia coli (E. coli) (18, 25). A fluorescently labeled substrate, MCA-AVLQ SGFR-Lys...More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against Dihydrofolate reductase enzyme purified from Plasmodium berghei.More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The assays are from references cited in this article.More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufuMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataIC50: 858nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataEC50:  720nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataEC50:  720nMMore data for this Ligand-Target Pair
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TargetReplicase polyprotein 1ab(2019-nCoV)
A*STAR

LigandPNGBDBM420297(acs.jmedchem.1c00409_ST.30 | med.21724, Compound 6...)copy SMILEScopy InChI
Affinity DataEC50:  330nMAssay Description:This is a review article.More data for this Ligand-Target Pair
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