Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM448272'
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:The enzymatic inhibition assay was carried out with a final concentration of 100 nM recombinant SARS-CoV-2 Mpro and 20 μM FRET substrate. For th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B34C1PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)copy SMILEScopy InChI
Affinity DataEC50:  1.20nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B34C1PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)copy SMILEScopy InChI
Affinity DataEC50:  35nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B34C1PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Sichuan University

LigandPNGBDBM448272(MI-09)copy SMILEScopy InChI
Affinity DataEC50:  860nMAssay Description:The differential scanning fluorimetry (DSF) assay was carried out on a CFX96 real-time PCR Detection System (Bio-Rad). All the experiments were perfo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B34C1PubMed