Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM49122'
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR
TargetReplicase polyprotein 1ab(2019-nCoV)
Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP) and Fraunhofer Cluster of Excellence for Immune mediated diseases (CIMD)

LigandPNGBDBM49122(2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propi...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Primary assay principle based on quenched FRET peptide substrate of SARS-CoV-2 3CL-Pro (lhs). Inhibiting compounds reduce fluorescence signal relativ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39VR