Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab' and Ligand = 'BDBM496839'
TargetReplicase polyprotein 1ab(2019-nCoV)
TBA

LigandPNGBDBM496839(SARS-CoV-2 PLpro Inhibitor, 69)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:The PLpro primary assay, which measures protease activity with the short peptide substrate Z-RLRGG-AMC (Bachem), was performed in black flat-bottom 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H1354MPubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
TBA

LigandPNGBDBM496839(SARS-CoV-2 PLpro Inhibitor, 69)copy SMILEScopy InChI
Affinity DataKd:  1.56E+3nMAssay Description:The His-tagged SARS-CoV-2 PLpro enzyme was initially prepared in phosphate buffer and diluted to 50 ug/mL with 10 mM sodium acetate (pH 5.5) and immo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H1354MPubMed