Found 5 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase/RNaseH' and Ligand = 'BDBM50106919' TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine
Curated by ChEMBL
University of Pittsburgh School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of FLAG-p66/HIS-p51-mediated HIV1 reverse transcriptase dimerizationMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine
Curated by ChEMBL
University of Pittsburgh School of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activityMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine
Curated by ChEMBL
University of Pittsburgh School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.38E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine
Curated by ChEMBL
University of Pittsburgh School of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.74E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine
Curated by ChEMBL
University of Pittsburgh School of Medicine
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cellsMore data for this Ligand-Target Pair
