Compile Data Set for Download or QSAR
Found 8 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50075204'
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by li...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant polymerase activity using [3H]TTP and poly(rA)-oligo(dT)16 substrate incubated for 20 mins by l...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end direc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in internal cleavage using HTS-1 RNA/D...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant associated RNase H domain activity assessed as reduction in reduction in DNA 3' end directed cl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50075204(CHEMBL3414868)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of Moloney murine leukemia virus reverse transcriptase polymerase activity using Td100/Pd18 DNA-DNA substrate incubated for 30 mins by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BWGPubMed