Compile Data Set for Download or QSAR
Found 4 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50164648'
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164648(2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...)copy SMILEScopy InChI
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD21R2PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164648(2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...)copy SMILEScopy InChI
Affinity DataKd:  1.54E+4nMAssay Description:Inhibition of DNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of dTMP by burst assay using DNA/DNA Pri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39Z3PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164648(2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...)copy SMILEScopy InChI
Affinity DataKd:  6.71E+4nMAssay Description:Inhibition of RNA-dependent DNA polymerase activity of HIV 1 reverse transcriptase assessed as incorporation of dTMP by burst assay using RNA/DNA Pri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ39Z3PubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
University of Pittsburgh School of Medicine

Curated by ChEMBL
LigandPNGBDBM50164648(2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...)copy SMILEScopy InChI
Affinity DataKd:  2.08E+3nMAssay Description:Binding affinity to wild type HIV1 LAI reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4MK7PubMed