Found 9 Enz. Inhib. hit(s) with Target = 'Reverse transcriptase' and Ligand = 'BDBM50467347' TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by MTT assayMore data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dGTP inco...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Competitive inhibition of C-Terminal histidine-tagged wild type heterodimeric HIV-1 reverse transcriptase p66/p51 assessed as inhibition of dTTP inco...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of HIV1 reverse transcriptase Y188L mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I mutant infected in human MT4 cells assessed as protection against virus-induced cytopathic effect by M...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N/Y188C double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
TargetReverse transcriptase(Human immunodeficiency virus 1)
Wuhan Institute of Technology
Curated by ChEMBL
Wuhan Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 798nMAssay Description:Inhibition of HIV1 reverse transcriptase L100I/K103N double mutant infected in human MT4 cells assessed as protection against virus-induced cytopathi...More data for this Ligand-Target Pair
