Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM252001'
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM252001(US9458110, 1)copy SMILEScopy InChI
Affinity DataIC50: 6.69nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F2WUS Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM252001(US9458110, 1)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Inhibition of ROCK1 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH peptide substrate by caliper assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969Z7PubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Company

US Patent
LigandPNGBDBM252001(US9458110, 1)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails