Found 1 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 1' and Ligand = 'BDBM50462716' TargetRho-associated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc
Curated by ChEMBL
Vertex Pharmaceuticals, Inc
Curated by ChEMBL
Affinity DataKi: 47nMAssay Description:Inhibition of ROCK1 (6 to 553 residues) (unknown origin) using Lys-Lys-Arg-Asn-Arg-Thr-Leu-Ser-Val as substrate by pyruvate kinase-lactate dehydrogen...More data for this Ligand-Target Pair
