Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM251935'
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM251935(US9458110, 7)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of ROCK2 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH peptide substrate by caliper assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J969Z7PubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM251935(US9458110, 7)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMpH: 7.5Assay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2F2WUS Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM251935(US9458110, 7)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails