Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Rho-associated protein kinase 2' and Ligand = 'BDBM299174'
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM299174(N-(2-(Isoindolin-2-yl)pyrimidin-4-yl)-1H-indazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9N5NUS Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM299174(N-(2-(Isoindolin-2-yl)pyrimidin-4-yl)-1H-indazol-5...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE Kinase Assay Kit (Invitrogen catalog number PV3793). Puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7KR6US Patent