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Affinity DataKi: 40nMAssay Description:Purified active ROCK1 and ROCK2 were obtained from Invitrogen (catalog numbers ROCK1, PV3691 and ROCK2, PV3759). The kit components include a coumari...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Millipore immuno-based 96 well plate assay (Millipore catalog number CSA001). Puri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Purified active ROCK1 and ROCK2 were obtained from Invitrogen (catalog numbers ROCK1, PV3691 and ROCK2, PV3759). The kit components include a coumari...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Dose response curves for Rho-kinase inhibition were derived from a Invitrogen Z′-LYTE™ Kinase Assay Kit (Invitrogen catalog number PV3793). Pur...More data for this Ligand-Target Pair
Affinity DataKd: 65nMAssay Description:Compounds were tested using an 11-point curve with 3-fold serial dilutions. IC50 determinations were made using an ATP concentration of 10 uM. The hi...More data for this Ligand-Target Pair
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