Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha-3' and Ligand = 'BDBM50568104'
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568104(CHEMBL4858257 | US11851436, Compound A1-2)copy SMILES
Affinity DataIC50: 24.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568104(CHEMBL4858257 | US11851436, Compound A1-2)copy SMILES
Affinity DataIC50: 56nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KKBPubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))TBA
LigandPNGBDBM50568104(CHEMBL4858257 | US11851436, Compound A1-2)copy SMILES
Affinity DataEC50:  970nMAssay Description:Inhibition of RSK2 in human MOLM-13 assessed as reduction in cell viability measured after 72 hrs by MTS assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KKBPubMed