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TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: 0.148nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: 0.148nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: 0.165nMAssay Description:Inhibition of recombinant human full-length N-terminal Flag epitope-tagged ATR expressed in HEK293T cells using ASELPASQPQPFSAKKK peptide as substrat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: 0.200nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: 0.200nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <1nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <1nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <1nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <1nMAssay Description:Compounds can be screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays are carried out in a mixt...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <10nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataKi: <10nMAssay Description:Compounds were screened for their ability to inhibit ATR kinase using a radioactive-phosphate incorporation assay. Assays were carried out in a mixtu...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant FLAG-tagged full length ATR expressed in mammalian cell line co-expressing human recombinant cMyc-tagged full length ...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
VERTEX PHARMACEUTICALS INCORPORATED
US Patent
Affinity DataIC50: 19nMAssay Description:Inhibition of ATR in human HCT116 cells assessed as reduction in histone H2AX phosphorylation by Hoechst staining-based immunofluorescence microscopi...More data for this Ligand-Target Pair
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