Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase ATR' and Ligand = 'BDBM50427296'
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427296(CHEMBL2325440)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of ATR-mediated CHK1 phosphorylation at serine 345 in human HT29 cells after 1 hr in presence of 4-nitroquinoline 1-oxideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q5CPubMed
TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50427296(CHEMBL2325440)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of ATR-mediated CHK1 phosphorylation at serine 345 in human HT29 cells after 1 hr in presence of 4-nitroquinoline 1-oxideMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q5CPubMed